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A modelling study based on satellite observations, machine learning and a chemical transport model quantifies the global and regional exposure to particulate-matter pollution and the human health impacts related to the 2023 Canadian wildfires.
A rhynchocephalian skeleton around 3–7 million years older than the oldest currently known lepidosaur fossil provides important insight into the origin of lizards and snakes.
The results from a state-of-the-art suite of hydrodynamical cosmological zoom-in simulations show how globular clusters naturally emerge in the Standard Cosmology and also reveal the existence of a new class of object called globular-cluster-like dwarfs.
Establishing antisense oligomers as versatile, non-genetic tools to silence phage mRNAs opens applications in basic research and biotechnology, as shown by identifying essential factors for propagation of the nucleus-forming jumbo phage ΦKZ such as the RNase H-like protein ΦKZ155.
Amino acids possess a new and broad colloidal property: they stabilize patchy nanoscale colloids, such as proteins, by adsorbing onto their surfaces through weak interactions.
Red light- or ultrasound-controlled proximity labelling is engineered to stimulate clustering-induced receptor activation and downstream signalling amplification to promote antitumour immune responses.
Loss-of-function variants of ABCA7, associated with Alzheimer’s disease, result in disrupted lipid metabolism, mitochondrial function, DNA repair and synaptic signalling pathways in the human brain.
Glutamatergic and GABAergic (γ-aminobutyric acid-producing) cortical neuronal activity drives proliferation of small lung cell cancer via paracrine interactions and through synapses formed with tumour cells.
Analysis of samples from the asteroid Ryugu provide evidence of late fluid flow in a carbonaceous asteroid, indicating that such bodies may have retained two to three times more water than previously thought.
Unbiased clustering analysis of the skeletal muscle RNAome in patients with cancer identifies two molecular subtypes, one of which distinguishes individuals with cachexia and indicates potential target pathways for future research.
Resonant inelastic X-ray scattering can be used to measure the spin current carried by magnons in the presence of temperature gradients across a magnetic insulator.
Climate change made 213 historical heatwaves reported over 2000–2023 more likely and more intense, to which each of the 180 carbon majors (fossil fuel and cement producers) substantially contributed.
A geological, petrographic and geochemical survey of distinctive mudstone and conglomerate outcrops of the Bright Angel formation on Mars reveals textures, chemical and mineral characteristics, and organic signatures that warrant consideration as potential biosignatures.
An understanding of the molecular mechanisms promoting the generation of immunoregulatory and tumour-promoting monocytes and macrophages is key to breaking the cycle of tumour myelopoiesis and developing more effective myeloid-targeting therapies.
Using 19F nuclear magnetic resonance to study LiF–LiH solid solutions revealed that it is present in the solid–electrolyte interphase of lithium metal batteries and confirms the heterogeneous nature of LiF in such interphases.
Small cell lung cancer cells form functional synapses with glutamatergic neurons, receiving synaptic transmissions and deriving a proliferative advantage from these interactions.
