Variations in Pathways by Which Equine Encephalomyelitic Viruses Invade the GNS of Mice and Guinea-pigs

@article{Sabin1938VariationsIP,
  title={Variations in Pathways by Which Equine Encephalomyelitic Viruses Invade the GNS of Mice and Guinea-pigs},
  author={Albert B. Correspondence Sabin and Peter K. Olitsky},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  year={1938},
  volume={38},
  pages={595 - 597},
  url={https://api.semanticscholar.org/CorpusID:86957184}
}
  • A. SabinP. K. Olitsky
  • Published 1 May 1938
  • Biology, Medicine
  • Proceedings of the Society for Experimental Biology and Medicine
It is remarkable, however, that in these mice the localization of lesions practically always corresponded to some definite pathway, suggesting that the virus was set free in one focus from which it spread along the nervous pathways connected with it (excepting the olfactory pathway).

The effect of vaccines and other substances upon the course of neurotropic virus infection

Intracerebral inoculation of vaccines, and to a lesser extent other substances, increased mortality in mice which had received intramuscular inoculations of GDVII virus, by allowing virus to pass directly from the blood into the brain.

Equine Encephalomyelitis in Infancy.

This disease is particularly worthy of consideration by pediatricians in the differential diagnosis of febrile disorders associated with encephalitic manifestations, especially during the summer and fall months in those areas where encephalomyelitis has been known to occur among horses.

On the affinity of a few strains of encephalitis virus to various organs of mice, especially brain and blood, comparisons being made with that of Negishi strain.

Process and mechanism of the infection exercised by the virus and the host, therefore, are the most essential aspects for evaluating such theory.

Studies on West Nile virus infection by means of fluorescent antibodies

Nervous tissue and mesenchymal tissue appeared to show equal susceptibility to primary viral invasion and growth, and the possibility that the blood vessel wall is one of the primary sites of multiplication for WN virus is suggested.

Viral Infections of the Human Nervous System*

The development by Enders and his associates of satisfactory serologic methods for diagnosis not only established the truth of this suspicion of mumps meningitis, but provided unequivocal proof that the nervous system is not infrequently affected by viruses.

Concepts of the Immunology of Certain Virus Infections.

Serum antibody such as agglutinin, precipitin and complement-fixing and neutralizing, can be elicited: the statement that virus infections are followed by a lasting immunity to reinfection has many exceptions-repeated or second attacks of common cold, herpes, influenza, foot-and-mouth disease, phlebotomus fever, poliomyelitis and other virus diseases are recorded.

Pathogenesis of neurotropic arbovirus infections.

Human infections and the disease in wild rodents, birds, and domestic animals were studied in relation to viremia and distribution of the infectious agent in the organism.

Feasibility of Aerosol Vaccination in Humans

It is concluded that aerosol immunization seems a promising method of vaccination that has already been used successfully in large populations and has passed the phase of initial feasibility evaluation.

The pathogenesis of viral infections of the nervous system.

IN 1936 Hurst's1 review of the pathogenesis of virus disease of the nervous system crossed the boundaries of traditional disciplines by "taking into account both the viruses and the terrain on whic...